In this episode of The Bioactive Nexus podcast, Dr. Bill Clark and Dr. Gene Bruno delve into the critical topic of cognitive function, particularly as it relates to aging and the growingmarket for brain health supplements. They discuss the importance of understanding cognitive function's subdomains, such as memory and attention, and explore the mechanisms of action that underpin various nutraceuticals. The conversation highlights market trends, key ingredients for cognitive support, and the significance of formulation strategies that consider consumer expectations. The episode concludes with insights into future topics, including the role of psychedelics in cognitive health and the importance of gut health for brain function.

Keywords

cognitive function, brain health, nutraceuticals, neuroplasticity, aging, supplements, mechanisms of action, market trends, formulation strategies, consumer expectations

Takeaways

· Cognitive function is crucial as we age.

· Neuroplasticity allows the brain to reorganizeitself.

· The nootropics market is rapidly growing.

· Different mechanisms of action should be used informulations.

· Realistic consumer expectations are essentialfor product success.

· Gut health significantly impacts cognitivefunction.

· Psychedelics are gaining attention in cognitivehealth research.

· Formulation strategies should avoid the kitchensink approach.

· Clinically relevant doses are necessary foreffectiveness.

· Brain health requires a long-term commitment.

Chapters

00:00 Introduction to Cognitive Function and Aging

07:16 Understanding Cognitive Function and Neuroplasticity

12:04 Market Trends in Brain Health Supplements

18:17 Mechanisms of Action in Cognitive Health

20:06 Key Ingredients for Cognitive Enhancement

21:46 Exploring Cognitive Enhancers: Lion's Mane and Ginkgo Biloba

23:21 The Power of Caffeine and Theanine

25:04 Omega-3s and Spermidine: Essential Nutrients for BrainHealth

26:53 Emerging Ingredients: Uridine Monophosphate and PQQ

28:49 The Role of Sage and Nicotinamide Riboside inCognitive Function

30:46 Neuroprotective Polyphenols: Blueberries and Curcumin

32:07 Formulation Strategies: Synergy and Dosing

35:23 Navigating Nootropic Claims: Real vs. Hype

38:56 Building Brand Loyalty Through Realistic Expectations

41:14 Final Takeaways: The Long Game of BrainHealth

In this conversation, experts discuss the implications ofGLP-1 receptor agonists like Ozempic in the context of weight loss and the supplement industry. They explore the mechanisms of GLP-1, the importance of diet and exercise, and the challenges faced by individuals using thesemedications. The panelists emphasize the need for a comprehensive approach to obesity, including dietary changes and physical activity, while also addressingthe role of natural products and emerging research in metabolic health. They conclude with thoughts on the future of weight management and the importance of consumer education in navigating the supplement landscape.

Please see the links below for more information on our guests’ companies.

• Dr. Jacqueline Jacques, ND – Wellness Industry Expert, obesity specialist, vocal critic of “natural Ozempic” claimso https://www.bariatricadvantage.com/o https://www.mvpnutra.net/o https://shop.myeq.com/

• Jim Ayres – CEO of Kelker Pharma, product development and contract manufacturing leadero https://kelkerpharma.com/

• Dr. Luc Maes, ND – Founder of KAIBAE, expert in gut–metabolic axis, polyphenols, and microbiome scienceo https://maescenter.com/o https://www.baobabingredients.com/o https://gokaibae.com/

• Michael Bengivenga – SVP, New Business Development Vitaworks, experienced in brand and commercial development in the supplement spaceo https://vitaworksusa.com/

In this conversation, Dr. Gene Bruno and Dr. Bill Clark explore the twelve hallmarks of aging, discussing how each hallmark impacts health and longevity. They delve into the role of nutraceuticals in addressing these hallmarks, emphasizing the importance of genomic stability, telomere length, epigenetic alterations, and more. The discussion highlights the interconnectedness of these factors and their implications for maintaining health as we age.

In this episode, Dr. Gene and Dr. Bill discuss the multifaceted topic of sexual dysfunction and the role of various supplements in addressing it. They explore the prevalence of sexual dysfunction, the importance of a holistic approach that includes diet, exercise, and emotional health, and delve into specific supplements such as amino acids, botanicals, and hormones. The conversation highlights emerging research on ingredients like black ginger and the significance of using standardized, effective products for optimal results.

In this episode, Dr. Bill and Dr. Gene discuss the critical topic of healthy aging, exploring various aspects such as immune function, antioxidants, inflammation, and metabolic processes. They delve into the importance of dietary supplements and nutraceuticals in promoting longevity and overall wellness. The conversation highlights key ingredients like vitamin D, omega-3 fatty acids, curcumin, creatine, magnesium, and spermidine, emphasizing their roles in enhancing health as we age. The episode concludes with insights into emerging trends and future directions in the field of healthy aging.

In this deep dive conversation in The Bioactive Breakdown series, Dr. Bill, Dr. Gene and expert guests discuss the topic of hepatotoxicity in dietary supplements, particularly focusing on the implications of recent studies and media reports. They emphasize the importance of understanding the difference between correlation and causation, the challenges of self-reported dietary surveys, and the need for consumer awareness regarding supplement safety. The discussion also highlights the significance of clinical research in assessing liver health and the role of reputable brands in ensuring product safety and efficacy.

In this episode of The Bioactive Insight, Dr. Gene and Dr. Bill celebrate Valentine's Day while discussing the importance of heart health. They delve into various nutraceuticals that can support cardiovascular health, including omega-3 fatty acids, antioxidants, turmeric, CoQ10, and more. The conversation also covers the role of diet, exercise, and stress management in maintaining heart health, emphasizing a comprehensive approach to wellness. Listener questions are addressed, providing insights into genetic predispositions and the benefits of magnesium and CoQ10.

In this episode, Dr. Bill, Founder & CEO of NutriSelectAI, and Dr. Gene discuss the upcoming launch of NutriSelectAI, an innovative app designed to empower consumers in the dietary supplement industry. They explore the challenges consumers face, including misleading claims and the overwhelming number of products available. The conversation highlights the importance of transparency, scientific validation, and personalized recommendations inimproving consumer trust and health outcomes. The hosts envision a future where NutriSelectAI transforms the industry by providing reliable information and fostering accountability among product brands.

Visit NutriSelectAI and presubscribe at: www.nutriselect.ai