In this episode of Optimize W(e), host Lindsay O’Neill welcomes Joseph Krieger, founder of Boston Biolife, for a deep dive into the world of regenerative medicine, biohacking, and patient empowerment. With over 25 years in healthcare and life sciences, Krieger shares how his unconventional path—from biochemistry labs to medical device innovation—shaped his mission to bring cutting-edge science into everyday clinical practice. He pulls back the curtain on the inefficiencies of traditional medicine, the promise of orthobiologics, and why inflammation might be the root of all disease.

Through personal stories and sharp insights, Krieger challenges the status quo and makes a compelling case for personalized, proactive health. Whether he’s harvesting fat in a hotel cadaver lab or advocating for smarter surgical decisions, his core message is clear: take ownership of your body and be curious enough to question everything. If you're ready to rethink what’s possible in medicine and optimize your health from the inside out, this episode is your blueprint.

In this compelling episode of Optimize W(e), host Lindsay O'Neill sits down with Jessica MacNaughton, CEO and Co-founder of C60 Power, to explore the transformative world of biohacking and personal health responsibility. Jessica’s journey from a high-powered commercial real estate career to the wellness industry was sparked by her own battle with adrenal burnout. Her experience led her to question conventional medicine, embrace biohacking as a tool for self-optimization, and champion a proactive approach to health.

Together, Lindsay and Jessica dive into the limitations of modern healthcare—especially its neglect of nutrition—and highlight the essential role of supplementation in today’s world. The conversation takes a deep dive into Carbon 60 (C60), a powerful antioxidant known for its ability to neutralize oxidative stress, optimize mitochondrial function, and support overall well-being. Jessica breaks down the science behind C60 and shares how C60 Power ensures the highest purity in its oils, skincare products, pet supplements, and more. Lindsay even shares her personal success stories, from glowing skin to improved energy and vitality.

Beyond C60, the discussion touches on foundational health principles, including the benefits of sun exposure, the dangers of seed oils, and why critical thinking is essential in the often-overwhelming biohacking space. Jessica encourages listeners to be discerning consumers, conduct their own research, and take ownership of their health journey—because no one understands your body better than you do.

If you’re curious about cutting-edge wellness strategies, seeking practical health insights, or looking for ways to take control of your well-being, this episode is a must-listen. Tune in to discover how to optimize your health with science-backed strategies and expert insights!

In this powerful episode of Optimize W(E), host Lindsay O’Neill sits down with her fiancé, Daniel O’ Keefe—an FDNY Lieutenant, decorated firefighter, and relentless biohacker. With over two decades of service, O’Keefe shares firsthand accounts of the physical and emotional toll firefighting takes, from carrying 100 pounds of gear into burning buildings to enduring a dozen surgeries and life-altering injuries.

But his story doesn’t end with hardship—it’s one of resilience, healing, and innovation. Lindsay and Daniel dive deep into his journey of recovery through cutting-edge biohacking techniques, holistic health practices, and the power of mindset, faith, and love. From red light therapy to the simple yet profound benefits of sunlight, sleep, and grounding, this conversation is packed with actionable insights for anyone looking to optimize their well-being.

Join us for a heartfelt, raw, and inspiring discussion about service, survival, and the science of healing—both inside and out.

In this compelling episode, Lindsay and her guest, Samantha Lander, share their deeply personal health journeys, uncovering unexpected twists that transformed their understanding of well-being. Lindsay’s shocking experience of teething for the first time at 43 led her to explore biological dentistry, revealing the profound connection between oral health and overall wellness. Meanwhile, Samantha—a single mother, biohacker, and former personal trainer—opens up about her struggles with chronic illness, addiction, and even incarceration. Within prison walls, she found an unexpected sense of purpose, working with heavy machinery and discovering resilience. However, her ongoing battles with gut issues, cystic acne, and the long-term effects of antibiotic use eventually pointed her toward functional medicine and self-testing, where she unearthed hidden food sensitivities and parasitic infections. Her relentless pursuit of answers not only improved her health but also led her to create a business dedicated to helping others navigate their own healing journeys.

The conversation takes a powerful turn as Samantha recounts her two-and-a-half-year struggle with a severe tooth infection that wreaked havoc on her body—causing sinus issues, nerve pain, and relentless brain fog. Despite multiple dental procedures and surgeries, relief only came when she embraced biological dentistry, experiencing a dramatic improvement in her health. Beyond physical healing, both Lindsay and Samantha reflect on the emotional and spiritual aspects of their journeys—how chronic illness has shaped their roles as mothers, tested their faith, and fueled their determination to help others. They discuss biohacking techniques, holistic healing methods, and the power of mindset in overcoming obstacles. As Samantha takes a much-needed break to reassess her path, she considers a new calling as a "mouth counselor," helping others heal from traumatic medical experiences.

Lavinia Errico, the visionary co-founder of Equinox gyms and now the creator of Move Joy, joins Lindsay to discuss her groundbreaking approach to fitness and well-being. Lavinia recounts the early days of Equinox in the 1990s, where she and her siblings transformed the New York City fitness landscape by creating an experience that rivaled the appeal of happy hour. They focused on cultivating a vibrant atmosphere with dynamic lighting, energizing music, and passionate instructors, fostering a strong sense of community that inadvertently revitalized the Upper West Side. Lavinia's journey then shifts to her current focus on Move Joy, a movement class designed to release energy, promote well-being, and cultivate joy. She emphasizes the importance of integrating spiritual practices like meditation and manifestation into fitness, recognizing the interconnectedness of physical, mental, and emotional health. Both Lavinia and Lindsay highlight the power of breathwork and mindful movement in releasing negative emotions and promoting overall vitality. They delve into specific movement techniques, including deep breathing, sweeping arm movements, and spine-twisting exercises, all aimed at oxygenating cells and stimulating the body. Lavinia shares personal anecdotes of using these techniques to navigate emotional stress and transform her mindset, underscoring the role of joy as a potent biohack. The conversation touches on the need for the fitness industry to shift its focus from shame-based approaches to those that prioritize self-love and joy, particularly for deconditioned individuals. Lavinia discusses the launch of her Move Joy app, which aims to make these transformative movement practices accessible to a wider audience. They conclude by celebrating the power of a smile and the importance of maintaining a youthful spirit through movement and positive energy.

Welcome to the first episode of Optimize W(e) with host Lindsay O'Neill. This week's guest is Brandy Shapiro-Babin. Together Lindsay and Brandy explore the fascinating world of optimizing biology for maximum health. They delve into actionable health data and its application in navigating various life stages, from perimenopause and hormonal changes to the unique challenges faced by men. Lindsay and Brandy unpacked the pervasive impact of inflammation and the constant battle against toxins in our food, while also highlighting the often-overlooked importance of sexual health in overall well-being.

Throughout this episode, Lindsay and Brandy share their personal health journeys, including their struggles with chronic illness and autoimmune issues. They underscore the importance of self-care, education, and community support in the pursuit of wellness. Lindsay also introduces her platform, WellnessEternal, dedicated to educating individuals about safe and effective products and services for optimal health. Enjoy today’s show and don’t forget to check back for more episodes as we embark on a journey of discovery, empowerment, and a shared commitment to a healthier, more vibrant life.

In this episode of Optimize W(e), host Lindsay O’Neill sits down with filmmaker, nutrition expert, and Food Lies creator Brian Sanders for a deep dive into the truth about food, fitness, and well-being. Lindsay and Brian share their personal health journeys—how loss and life-changing realizations led them to challenge mainstream nutrition narratives and embrace a more intentional way of eating and living.

From debunking common diet myths to practical meal-planning tips, they explore how simple shifts—like cutting out processed foods and embracing ancestral health—can lead to transformative results. They also discuss the role of community, nature, and even karaoke in maintaining a balanced and fulfilling life.

Tune in for an eye-opening conversation that will inspire you to rethink your relationship with food, movement, and happiness. Plus, get a sneak peek into Brian’s Food Lies documentary and upcoming speaking engagements at the Health Optimization Summit!