『Listen, Learn, Adapt』のカバーアート

Listen, Learn, Adapt

Listen, Learn, Adapt

著者： Anthony Novello
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このコンテンツについて

 In each episode, one research article will be dissected in plain, clear language—no opinions, just evidence. We will do a deep dive into the world of health & wellness, physical medicine & rehab, and pain. The focus is on detailed explanations that help you understand the evidence and apply it to real life. Whether you're an athlete, a healthcare provider, someone who enjoys staying informed, or just getting started with health and wellness, this podcast makes research easy to follow, digest, and use—without the jargon. Dr. Anthony Novello, PT, DPT https://www.instagram.com/anthonynovello.dpt/Anthony Novello
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  • 5: Creatine Supplementation: Brain Health and Function

    5: Creatine Supplementation: Brain Health and Function
    2025/06/04

    This review article explores the potential benefits of creatine supplementation for brain health and function. It summarizes current research showing that creatine can increase brain creatine stores, potentially improving cognition and memory, especially under metabolic stress or in aging adults. The paper also discusses promising effects of creatine in managing symptoms associated with traumatic brain injuries, muscular dystrophies, depression, and anxiety.


    Candow DG, Forbes SC, Ostojic SM, et al. "Heads Up" for Creatine Supplementation and its Potential Applications for Brain Health and Function. Sports Med. 2023;53(Suppl 1):49-65.

    doi:10.1007/s40279-023-01870-9


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    16 分
  • 4: Strength Training, Telomere Length, and Biological Aging

    4: Strength Training, Telomere Length, and Biological Aging
    2025/06/01

    This academic paper from the journal Biology presents research investigating the relationship between strength training frequency and telomere length, a marker of biological aging, in a large, representative sample of U.S. adults.


    Tucker LA, Bates CJ. Telomere Length and Biological Aging: The Role of Strength Training in 4814 US Men and Women. Biology (Basel). 2024;13(11):883. doi:10.3390/biology13110883


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    16 分
  • 3: Neuronal Senescence in Dorsal Root Ganglia and Pain

    3: Neuronal Senescence in Dorsal Root Ganglia and Pain
    2025/05/29

    This scientific paper explores the phenomenon of neuronal senescence in the dorsal root ganglia (DRG), which are clusters of nerve cells involved in sensory perception. The research demonstrates that aging and peripheral nerve injury both contribute to the accumulation of senescent neurons in the DRG of mice and humans. These senescent neurons are found to express pro-inflammatory markers like IL6 and exhibit altered electrical excitability, particularly in nociceptors, which are pain-sensing neurons. Crucially, the study shows that targeting and removing these senescent cells with a senolytic drug can improve pain-related behaviors, suggesting a potential therapeutic avenue for treating chronic pain, especially in older individuals.


    Donovan, L.J., Brewer, C.L., Bond, S.F. et al. Aging and injury drive neuronal senescence in the dorsal root ganglia. Nat Neurosci 28, 985–997 (2025). https://doi.org/10.1038/s41593-025-01954-x


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    23 分

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