In this episode we look at a relatively old industrial fix: the use of nitrite—a toxic chemical—for curing processed meat on a large scale. It’s a compelling case study to explore how regulatory policies are shaped and the complex role science plays in that process.
Our guest, Dr. Jérôme Santolini, a biochemist and research director at the Institute for Integrative Biology of the Cell at the University of Paris-Saclay, heads the Oxidative Stress and Detoxification Laboratory. He tells us about the biotoxicological mechanisms behind using nitrite to preserve meat and uncovers the historical origins of why a known poison became a key tool in food preservation.
Jérôme sheds light on the intricate roles nitrites (and other nitric oxides) play in the human body, their effects, and their potential carcinogenic risks. He also offers his perspective on how we can approach meat curing—and eating—more thoughtfully. Drawing on the lessons of the failed nitrite regulation in France, he advocates for a more reflective approach to knowledge production: one that prioritises deep understanding over the relentless pursuit of data – a proposition that is relevant far beyond the example of meat curing.
For additional resources and a deeper exploration of Jérôme’s work and views, please visit:
https://www.i2bc.paris-saclay.fr/equipe-oxidative-stress-and-detoxication/
https://theconversation.com/profiles/jerome-santolini-513994/articles
Further reading:
Coudray, G. (2023). Nitrites dans la charcuterie: Le scandale. New York: HarperCollins.
Coudray, G. (2021). Who Poisoned Your Bacon? The Dangerous History of Meat Additives. London: Icon Books .
Santolini, Jérôme. (2023). Additifs nitrés dans les charcuteries : quelle information scientifique pour quelle politique publique ?
Santolini, Jérôme; Steinberger, Julia. (2022). La désobéissance civile des scientifiques est justifiée sur les plans éthique et pragmatique. Le Monde.
Scientifiques en rébellion. (2024). Sortir des labos pour défendre le vivant. Paris: SeuilLibelle.
Stengers, I. (2015). In catastrophic times: Resisting the coming barbarism. London: Open Humanities Press.
Beyond the Fix is brought to you by Critical Scientists Switzerland, an independent network of scientists. It is made possible by the Stiftung Mercator Schweiz and produced by Podcastschmiede. Host: Thomas Kobel. Music: Mich Gerber.
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