エピソード

  • 42. Hell on Earth: Surviving a Cult Exile, OCD, ADHD & Life-Threatening Illnesses with Alie Bernard Garza, LCSW
    2025/06/02
    On episode 42, I sit down with my dear friend, Alie Bernard Garza, LCSW—a therapist, advocate, & survivor whose life reads like an impossible novel: childhood autoimmune disease, undiagnosed OCD & ADHD, a high-control evangelical cult, multiple psychiatric hospitalizations, near-death medical crises, & eventually, a 38/40 Y-BOCS spiral that forced her into residential ERP. That would be more than enough for most lifetimes—yet in 2022, she suffered a ruptured brain aneurysm that turned her worst health-OCD fears into terrifying reality. In this raw, unfiltered, & morbidly hilarious conversation, Alie tells the truth about what it's like to live inside a brain that won’t stop screaming—& how she finally found peace, purpose, & power on the other side.Alie Bernard Garza, LCSW, is a specialist in the treatment of OCD & anxiety-related disorders based in Denver, Colorado. She holds an MSW, has worked across all levels of care—IOP, PHP, residential, & inpatient, & is deeply committed to neurodivergent-affirming care, particularly for individuals with ADHD & Autism. Alie also specializes in supporting parents, families, adolescents, & young adults as they navigate complex mental health challenges. Through her own lived experience of severe OCD & advocacy, Alie brings both professional expertise & a deeply personal understanding to her work.Topics Discussed (+ Timestamps):(00:00:00) Introduction & welcome to Alie!(00:06:20) Who is Alie? Cackling loudly, caring deeply, and keeping it real(00:17:10) Little Alie: Ontario winters, early-onset autoimmune illness, & toddler OCD traits(00:21:00) School refusal, character shaming, and the fallout of mislabeling neurodivergence(00:27:30) Baby carrot fingers, Harm OCD, robot-Dad obsessions, & mental compulsions in silence(00:31:35) Health OCD, bent-knee lip-syncing, & OCD invisibility in high school(00:38:00) How a youth-ministry cult fulfilled every OCD need for certainty & hyperresponsiblity(00:45:00) Age 15 inpatient psych stay, OCD diagnosis, depression & suicidality, & being incorrectly treated with hypnosis(01:00:00) Alternative high school pivot & graduating early(01:10:00) Evangelical college, gallstone crash, and inpatient hell at 17(01:17:00) Harm OCD meets ministry work: “swerve the car” & looping thoughts(01:27:00) Excommunicated: blacklisted as “dangerous,” unraveling in isolation(01:35:00) Youth residential jobs, MSW training, and surviving without treatment(01:42:00) COVID collapse: health OCD, full agoraphobia, extreme OCD, & being unable to eat or drink(01:49:00) Finally accessing evidence-based OCD treatment, residential treatment saving her life, becoming an OCD specialist(02:05:09) Near-fatal brain aneurysm: when your worst health nightmare obsession becomes reality, and how OCD treatment saved her life(02:10:49) Launching OCD & Anxiety Colorado, neurodivergent-affirming family-inclusive IOPs, & creating the resources that she once neededConnect with Alie!WebsiteInstagram: @Alie.Garza, @OCDAnxietyColoradoLinkedIn: Alie, OAPEmail: alie@ocdanxietycolorado.com⁠⁠⁠Try CURED Nutrition's CBN Night Oil, Serenity Gummies, & all of their other fantastic products--Use code 'UMA' for 15% off of all products!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Try CLEARSTEM's amazing skincare products, including VITAMINSCRUB, CELLRENEW, CLEARITY, HYDRAGLOW, and HYDRABERRY--Use code 'UMA' for 15% off all products!⁠⁠⁠⁠⁠Connect with me!My website⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Support my work:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ko-fi.com/umarchatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Have a guest you want on the show? Fill out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Guest Suggestion Form!⁠
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    2 時間 37 分
  • 41. Mapping The Bipolar Brain: Emerging Biomarkers, New Brain Regions, & Lived Experience in Research with Dr. Maya Schumer
    2025/05/26
    On episode 41 of A Chat with Uma, we pick up right where we left off with Dr. Maya Schumer—a psychiatric neuroscientist who studies bipolar disorder, the very illness she lives with. In Part 2, Maya walks us through her PhD and Postdoc research thus far: the largest functional-MRI meta-analysis ever published at the time, 3 independent risk-cohort replications, and analyzing first-episode mania datasets. We dig into the honest reality of doing cutting-edge science while your brain is the very object of study—managing chronic suicidality, navigating disclosure, unlearning internalized (& reinforced) stigma, and redefining resilience beyond survival. Dr. Maya Schumer is a psychiatric neuroscientist & postdoctoral researcher who studies—& has lived experience with—Bipolar Disorder. Maya received her PhD in neuroscience from the University of Pittsburgh School of Medicine in 2023 mentored by Dr. Mary Phillips, where she used task-based functional neuroimaging & coordinate-based meta-analysis to identify reproducible & replicable neural network markers of bipolar disorder risk. Currently, Maya is a postdoctoral fellow at McLean Hospital, an affiliate of Harvard Medical School. Mentored by Dr. Dost Öngür, Maya examines resting-state functional connectivity patterns & neural network dynamics across different stages & mood states in bipolar disorder, with an overall goal to model its dynamic nature.Topics Discussed (+ Timestamps):(00:00:00) Welcome back to Maya! Quick recap of Part 1 & why you need it for context! LISTEN HERE(00:09:20) How Maya survived a PhD while in hell: mentors, support, and scope-control(00:11:00) fMRI 101—bold signals, task vs. resting state, and default-mode rumination(00:14:58) The heterogeneity problem: why three decades of bipolar imaging rarely replicate(00:17:30) Building a 205-study meta-analysis & finding new network players in the neurobiology of bipolar disorder(00:24:46) The shocking shortage of mania/mixed-state scans—and why it matters for biomarkers(00:26:56) Young-adult risk cohorts & the 169-item Mood Spectrum Self-Report(00:29:54) Replicating mania- vs. depression-specific connectivity across three datasets(00:33:00) Maya’s postdoc research: first-episode mania, mixed states, & siblings at risk(00:41:36) Discovering a stigma-smashing research environment at McLean(00:44:24) From patient to PI: lining up K-award goals while battling urgency & perfectionism(00:59:00) Compliance vs. acceptance: managing stability without pathologizing every human feeling(01:05:50) Internalized ableism, masking mania, & the myth of “functional” bipolar(01:14:06) Time lost to our illnesses, managing the standards of academia, & recalibrating worth(01:20:00) When the work keeps you alive but the workload can kill you(01:38:00) How our illnesses are simultaneously sensationalized AND stigmatized (01:44:50) Final reflections: will to live, redefining resilience, & building a new future for our fieldConnect with Maya⁠LinkedIn⁠X/Twitter: ⁠@SchumerMaya⁠Read her research on ⁠ResearchGate⁠Email: ⁠maya.schumer@gmail.com⁠⁠⁠Try CURED Nutrition's CBN Night Oil, Serenity Gummies, & all of their other fantastic products--Use code 'UMA' for 15% off of all products!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Try CLEARSTEM's amazing skincare products, including VITAMINSCRUB, CELLRENEW, CLEARITY, HYDRAGLOW, and HYDRABERRY--Use code 'UMA' for 15% off all products!⁠⁠⁠⁠Connect with me!My website⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Support my work:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ko-fi.com/umarchatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Have a guest you want on the show? Fill out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Guest Suggestion Form!⁠
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    2 時間 5 分
  • 40. Why Is My Brain Trying To Kill Me?: Living With Bipolar 1 Disorder & Chronic Suicidality with Dr. Maya Schumer (pt. 1)
    2025/05/19
    On episode 40 of A Chat with Uma, I sit down with my dear friend Dr. Maya Schumer—a psychiatric neuroscientist who studies bipolar disorder, the very illness she lives with. She shares her full experience across 3 decades: growing up with a father with bipolar 1 disorder, how her own bipolar 2 diagnosis morphed into bipolar 1, several hospitalizations, her relationship with lithium, chronic suicidality, metabolic psychiatry, IV ketamine, TMS, & redefining "stability." If you've ever struggled with chronic suicidality, felt the weight of stigma in academia, or questioned what makes life worth holding onto—this conversation is for you. Maya’s story is one of survival, honesty, & the power of turning pain into purpose. Dr. Maya Schumer is a psychiatric neuroscientist & postdoctoral researcher who studies—& has lived experience with—Bipolar Disorder. Maya received her PhD in neuroscience from the University of Pittsburgh School of Medicine in 2023, where she used task-based functional neuroimaging & coordinate-based meta-analysis to identify reproducible & replicable neural network markers of bipolar disorder risk. Currently, Maya is a postdoctoral fellow at McLean Hospital, an affiliate of Harvard Medical School. Mentored by Dr. Dost Öngür, Maya examines resting-state functional connectivity patterns & neural network dynamics across different stages & mood states in bipolar disorder, with an overall goal to model its dynamic nature.Maya’s passion for research is informed by her own lived experience. In her role as a researcher with lived experience, she aims to address & dismantle the stigma surrounding serious mental illnesses (SMIs), make academia & research environments more inclusive & accommodating for those with disabilities; & advocate for meaningful co-production between individuals with lived experience & scientists.Topics Discussed (+ Timestamps):(00:00:00) Introduction & welcome to Maya!(00:14:00) Artist → neuroscientist plot-twist(00:17:46) Creativity, bipolar, & the Kaye Redfield Jamison spark(00:20:26) How & why we met on X/Twitter, defying the norms of academia, & building a movement together(00:26:30) Ableism in research spaces & how we fight back(00:31:34) Childhood in bipolar’s shadow: therapy at three & “casserole syndrome”(00:38:42) Stigma lessons, dignity, & mourning a living ghost(00:43:02) College crash: color-coding moods → diagnosis at 20(00:46:30) Types I & II, mixed states, spectrum—& living every corner of it(00:53:00) Compliance ≠ acceptance: owning the illness vs. just taking meds(01:05:52) Losing sleep, losing friendships, & the 24/7 second job of self-monitoring(01:17:46) Seasonal mood whiplash & March-mania defenses(01:22:54) Keto, & lithium 2.0(01:34:12) Daily IV ketamine infusions, accelerated TMS, & embracing pluralism(01:44:30) A brutally honest & necessary conversation about chronic suicidality + harm reduction(01:52:00) Redefining stability, building lived-experience science, & preview to part 2Connect with MayaLinkedInX/Twitter: @SchumerMayaRead her research on ResearchGateEmail: maya.schumer@gmail.com⁠Try CURED Nutrition's CBN Night Oil, Serenity Gummies, & all of their other fantastic products--Use code 'UMA' for 15% off of all products!⁠⁠⁠⁠⁠⁠⁠⁠Try CLEARSTEM's amazing skincare products, including VITAMINSCRUB, CELLRENEW, CLEARITY, HYDRAGLOW, and HYDRABERRY--Use code 'UMA' for 15% off all products!⁠⁠⁠Connect with me!My website⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Support my work:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ko-fi.com/umarchatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Have a guest you want on the show? Fill out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Guest Suggestion Form!⁠
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    2 時間 13 分
  • 39. What If I’m A Murderer?: 29 Hospitalizations, Taboo OCD Themes, & the Recovery Lifestyle with Tracie Ibrahim, LMFT, CST
    2025/05/12
    On episode 39 of A Chat with Uma, I invite my dear friend Tracie Ibrahim, LMFT, CST to tell her full survivorship story of 29 psychiatric hospitalizations, misdiagnoses of schizophrenia & homicidality, childhood abuse, & a mental-health system that nearly killed her—until she learned the name of the monster (OCD) & fought back with exposure & response prevention. Tracie’s journey, like her, is messy, punk-rock, & heartbreakingly human, all at once: sneaking out of locked wards, filing her own writ of habeas corpus at 15, raising three kids while “raw-dogging” her mental health, & finally transforming the shame of harm, suicidal, & contamination OCD into a career as NOCD’s Chief Compliance Officer & the Instagram beacon “@TabooTracie." If you’ve ever felt defective, dangerous, or beyond help, this episode is a hug, a battle cry, & a masterclass in radical self-acceptance.Tracie Ibrahim, LMFT, CST, has 20+ years of experience in providing mental health services. Her specialization is treating OCD, anxiety & related disorders & depression, alongside a spectrum of issues affecting the LGBTQIA+ community, & issues with sexual health & functioning. Her expertise has been utilized to create high-quality programs addressing the increasing need for evidence-based counseling interventions. Currently serving as NOCD's Chief Compliance Officer, Tracie focuses on creating & implementing evidence-based treatment & compliance programs. Her passion for OCD treatment & advocacy work stems from managing her own OCD for 40+ years & raising children with OCD, anxiety, depression & neurodiversity.Topics Discussed (+ Timestamps):(00:00:00) Introduction & welcome to Tracie!(00:10:06) “Who is Tracie behind the titles?”—hover-mom, punk soul, universal acceptor(00:15:00) The first cracks: magical-thinking OCD at age 4, nightmares, divorce(00:20:00) Abuse, police indifference, & a 10-year-old’s first involuntary hold(00:26:00) Cutting, suicidal rituals, being considered homicidal, misdiagnosis of schizophrenia(00:31:00) Oppositional defiance label → transfer to county lockdown(00:37:00) Life inside Camarillo State Hospital with a roommate who’d murdered her family(00:43:30) Filing a writ of habeas corpus—& winning her own release at 15(00:51:00) Surviving residential care, starting community college(00:56:30) Discovering ERP & real OCD on Google, self-experimenting with money exposures(01:03:00) Turning pain into purpose: training clinicians, supervising interns(01:10:30) From therapist to NOCD’s Chief Compliance Officer—scaling ethical care(01:19:00) TabooTracie is born: why she tackles pedophilia, harm & suicide themes online(01:24:00) Living proof: managing daily suicidal OCD while medication-resistant(01:30:40) Reconciling with grief, advocacy as turning pain into purpose, & raising children(01:37:50) The differences between pedophilia OCD vs. true pedophilia(01:46:30) The anatomy of intrusive thoughts, urges, and compulsions in plain language(01:52:00) Closing reflections, rapid-fire questionsConnect with Tracie!Instagram: @TabooTracieLinkedIn: Tracie Ibrahim, LMFT, CSTTry CURED Nutrition's CBN Night Oil, Serenity Gummies, & all of their other fantastic products--Use code 'UMA' for 15% off of all products!⁠⁠⁠⁠⁠⁠Try CLEARSTEM's amazing skincare products, including VITAMINSCRUB, CELLRENEW, CLEARITY, HYDRAGLOW, and HYDRABERRY--Use code 'UMA' for 15% off all products!⁠⁠Connect with me!My website⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Support my work:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ko-fi.com/umarchatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Have a guest you want on the show? Fill out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Guest Suggestion Form!⁠
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    2 時間 18 分
  • 38. Whoa, I Made It To 29! Birthday & Cancerversary Reflections, Answering Your 29 Questions
    2025/04/28
    On episode 38 of A Chat with Uma, I reflect on both my 29th birthday & 6th anniversary of my cancer diagnosis. I share a live, raw, completely unedited account of everything rising to the surface as I turn 29. I speak at length about the awe and gratitude I feel for still being here + alive, and remember how staying on this planet for this long once felt utterly impossible. I talk through the rapid transformation of life that has unfolded since cancer, and all the recovery and reckoning that has followed—how wildly different everything looks compared with anything I could’ve imagined. I speak candidly about my current state of being, including the full spectrum of emotions that arrive when my birthday and my cancerversary land back-to-back. I walk through body memories, survivor’s guilt, and the transformative power of letting loved ones celebrate me anyway. I share concrete examples of how meeting life with my authentic self keeps creating experiences I never thought were remotely possible.Next, I answer 29 questions from YOU—everything from my coffee lifestyle and metal concerts to the hardest parts of living with PTSD + OCD, from “doing enough” to what self-compassion actually looks like when it finally lands. Through these answers & my reflections, I explore the duality of existence, the astonishment of how life looks, and the awe of continuing to travel the continuum of human experience. Above all, this episode is a statement of love, gratitude, acceptance, and holding hope for every single beautiful human listening—especially through the darkest and most impossible moments you may live through.Topics Discussed (+ Timestamps):(00:00:00) Welcome & why I'm recording this episode(00:02:56) 29th birthday arriving alongside my 6th cancerversary(00:09:44) Flashbacks, survivor’s guilt, and “the body keeps the score” in real time(00:18:58) Gratitude vs. self-hatred, learning to let others celebrate me(00:26:30) April's somatic bodily memories from cancer, insomnia, and over-scheduling as avoidance(00:33:44) 29 Questions: Random things about me (coffee order, comfort food, favorite books/movies/TV/shows/podcasts, lazy Saturdays, random facts: synesthesia, perfect pitch, The Voice, opening for Morgan Wallen show)(00:47:48) 29 Questions: My non-work life (Midwest living, yes I'm married)(00:55:08) 29 Questions: Mental health/Lived Experience (living with PTSD + OCD, mental health red flags, self-compassion, funniest intrusive thought, small victory, busting the “high-functioning” myth, push vs. rest, relationship with medication)(01:08:06) 29 Questions: Q's for me as a scientist (psychedelic therapy, other new treatments I'm excited about, staying objective in research with my lived experience, if I were a neurotransmitter)(01:14:40) 29 Questions: Big-picture musings (spirituality post-cult, healing vs. recovery, advocacy beyond OCD, writing a book someday, doing “too much,” measuring “enough”)Try CURED Nutrition's CBN Night Oil, Serenity Gummies, & all of their other fantastic products--Use code 'UMA' for 15% off of all products!⁠⁠⁠⁠Try CLEARSTEM's amazing skincare products, including VITAMINSCRUB, CELLRENEW, CLEARITY, HYDRAGLOW, and HYDRABERRY--Use code 'UMA' for 15% off all products!⁠Connect with me!My website⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Support my work:⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ko-fi.com/umarchatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠Have a guest you want on the show? Fill out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Guest Suggestion Form!⁠
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    1 時間 24 分
  • 37. What IS a Psychedelic?: The Basics of Psychedelic Science
    2025/04/21
    On episode 37 of A Chat with Uma, I hit pause on the lived experience & nitty-gritty research and rewind all the way to Psychedelics 101: What exactly counts as a psychedelic? Why do ketamine and MDMA show up in the same conversations as LSD and psilocybin even though they work on totally different receptors? In this deep‑dive I define "mind-manifesting," untangle the three big branches of hallucinogens, give an extra basic chemistry crash course (Lego analogies included), and walk through the neurobiology that turns a few serotonin receptors into weeks of heightened brain plasticity. You’ll also hear why “set and setting” actually matter, how non‑hallucinogenic 5‑HT2A receptor compounds are storming drug development pipelines, and a rapid‑fire myth‑busting round that debunks everything from “natural equals safe” to “one trip and you might never come back.” By the end you’ll have a clear map of the molecules, mechanisms, and mind‑manifesting experiences that shape today’s psychedelic landscape—plus the language to call out sloppy headlines when you see them.Topics Discussed (+ Timestamps):(00:00:00) Welcome back & why it's long past time for a Psychedelics 101 primer(00:01:52) 1956 flash‑back: Osmond, Huxley, and coining “psychedelic”(00:03:54) Two scientific litmus tests—5‑HT2A receptor engagement and the subjective “mind‑manifesting” fingerprint(00:07:06) Meet the core four: LSD, psilocybin/psilocin, DMT/5‑MeO‑DMT, mescaline(00:10:36) Hallucinogen family tree—classical psychedelics vs. dissociatives vs. deliriants(00:13:54) Ketamine’s NMDA detour and why they are not psychedelics (but... are they though?)(00:16:40) MDMA as empathogens / entactogens—psychedelic "cousins" (again... are they?)(00:18:22) Why cocaine, meth, and opioids are not psychedelics(00:24:38) How scientists slice the pie differently: phenomenology, pharmacology, neurobiology(00:27:18) Psychoplastogens, metaplasticity, and the rise of non‑hallucinogenic 5‑HT2A receptor drugs(00:30:02) Chemistry crash course—tryptamines, ergolines, phenethylamines in Lego form(00:33:56) Nature‑grown vs. lab‑crafted, & pro-drugs(00:39:00) Dose, route, and how chemical compositions shape your trip(00:45:14) Receptor binding → signaling cascades → neuroplasticity(00:52:16) Default‑mode downshift, whole‑brain hyper‑connectivity, and the plasticity window(00:55:08) Set, setting, and why supportive containers slash bad‑trip rates(01:00:58) Myth‑busting lightning round—ketamine ≠ psychedelic, holes‑in‑brain, “natural = safe,” more(01:05:36) Key takeaways, why clear language matters, and a teaser for upcoming guest interviewsTry CURED Nutrition's CBN Night Oil, Serenity Gummies, & all of their other fantastic products--Use code 'UMA' for 15% off of all products!⁠⁠Try CLEARSTEM's amazing skincare products, including VITAMINSCRUB, CELLRENEW, CLEARITY, HYDRAGLOW, and HYDRABERRY--Use code 'UMA' for 15% off all products!Connect with me!My website⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Support my work:⁠⁠⁠⁠⁠⁠⁠⁠https://ko-fi.com/umarchatterjee⁠⁠⁠⁠⁠⁠⁠⁠Have a guest you want on the show? Fill out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Guest Suggestion Form!⁠
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    1 時間 10 分
  • 36. Everything You Need To Know About Scientific Research: Peer Review & Publishing Papers
    2025/04/14

    On episode 36 of A Chat with Uma, I continue the “Everything You Need to Know About Scientific Research” series by breaking down everything you need to know about peer review and publishing papers! Here, I unpack the journey from raw data to a peer‑reviewed paper—the stage where independent experts test every assumption, statistic, and conclusion before the work can stand as part of the scientific record. You’ll learn why publishing is incredibly competitive after everything navigated to get the grant in the first place, how different review models (single‑blind, double‑blind, open, and registered reports) work, and what safeguards exist to catch bias or outright fraud.

    We’ll also clear up common misconceptions—like who actually pays publication fees, what "peer review" actually means, whether industry can “buy” favorable results, and how to spot predatory journals that mimic the real thing. By the end, you’ll know how to read research headlines with a sharper eye and a fuller understanding of the system behind them.


    Topics Discussed (+ Timestamps):


    (00:00:00) Welcome back & why peer review is the gatekeeper after funding


    (00:01:28) Grants vs. journals: the true currency of scientific reputation


    (00:03:54) Peer‑review basics: single‑, double‑, open, and registered reports


    (00:06:56) Preprint servers—speeding collaboration and sowing public confusion


    (00:09:58) Wildly competitive acceptance rates of scientific journals


    (00:13:46) Impact factors, citation culture, and career stakes


    (00:15:46) The money side: article‑processing fees and why scientists don’t profit


    (00:21:46) Step‑by‑step through the review gauntlet, from desk rejection to “accepted”


    (00:29:28) Conflicts of interest, Big Pharma fears, and science’s self‑corrections


    (00:32:50) Predatory journals: red flags and how researchers avoid them


    (00:40:54) Replication challenges and the tools fixing them (preregistration, open data)


    (00:45:14) Myth‑busting lightning round: peer review, pay‑to‑publish, and dissent


    (00:46:14) Key takeaways for understanding peer review and the process of publishing papers


    Try CURED Nutrition's CBN Night Oil, Serenity Gummies, & all of their other fantastic products--Use code 'UMA' for 15% off of all products!


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    50 分
  • 35. Yes, I've Done Psychedelics, Part 2: From Psychonaut to Researcher
    2025/04/07
    On episode 35 of A Chat with Uma, I provide the long‑overdue follow‑up to my 2023 episode “Yes, I’ve Done Psychedelics: From Psychonaut to Researcher!” Two years (and many trips) later, I walk you through how psychedelics have woven themselves into my recovery from OCD, PTSD, and treatment‑resistant depression--and how my relationship to them has evolved. I’m candid about the depression pattern I now recognize: months of slow improvement, a frightening slide into suicidal exhaustion, and finally the “as‑needed biological intervention” of a macro‑dose psilocybin session.I share why I now treat psilocybin as an “as‑needed biological intervention,” how my move to Madison and recovery gains changed the cadence of those sessions, and how I’m learning to identify red‑flag symptoms earlier so I don’t wait until rock‑bottom. Throughout the episode I’m brutally honest about the hellish parts: intrusive‑thought torture, eye‑burning exhaustion, and the constant urge to postpone each dose because I hate the experience even while I depend on the after‑effects. I describe how each trip has dovetailed with psychotherapy treatment for OCD, PTSD, and depression, and what last week’s brutally intense—but surprisingly fast‑acting—trip has already done for my mental state. If you want a raw, first‑person account of using psychedelics to carve out months of functional life—and why I still need intensive mental health treatment, behavioral change, and a healthy life to continue through recovery—here it is in its fullest form. Listen to these contextual episodes first:⁠My Full Story: 0 to 26⁠My Mental Health Journey:⁠ Part 1,⁠ ⁠Part 2⁠, ⁠Part 3⁠, ⁠Part 4,⁠ ⁠Part 5⁠⁠Yes, I've Done Psychedelics: From Psychonaut to Researcher⁠The Ketamine Diaries:⁠ Part 1,⁠ ⁠Part 2⁠Topics Discussed (+ Timestamps):(00:00:00) Recapping Part 1 from two years ago, where I left off with ketamine treatments, and how today’s episode picks up from where we left off(00:02:40) Why I share these vulnerable stories, disclaimers on anecdotal use, and how personal experiences shape broader conversations about psychedelics(00:09:00) The ‘As‑Needed’ Psilocybin Plan: How I decided to approach psilocybin on a loosely scheduled basis, what “biological intervention” means to me... and why I still push it off(00:18:00) From Ketamine Insights to Psilocybin Sessions: Unpacking what daily ketamine “torture” taught me about intrusive thoughts, the mind‑body split, and rediscovering color in life(00:23:00) Facing Relapse & ‘Rock Bottom’ Warnings: Tracking my early warning signs of depression, the classic OCD loops, and learning to heed those signals before everything shuts down(00:34:00) Exploring how moving to Madison, a supportive environment, and evidence-based therapy widened the gap between needing trips, sometimes up to eight months; Recap of my trips since 2023(00:56:00) The Most Recent Trip (March 2025): A raw look at my week‑old session: the usual “hell” meets an unexpected flash of self‑compassion, plus the quicker‑than‑normal bounce‑back effect(01:07:00) The unique relief I'm already experiencing from this trip, small windows of joy, and final reflections on integrating future psychedelics with therapy and recoveryTry CURED Nutrition's CBN Night Oil, Serenity Gummies, & all of their other fantastic products--Use code 'UMA' for 15% off of all products!Connect with me!My website⁠: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok:⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@UmaRChatterjee⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@umarchatterjee.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Support my work:⁠⁠⁠⁠⁠⁠⁠⁠https://ko-fi.com/umarchatterjee⁠⁠⁠⁠⁠⁠⁠⁠Have a guest you want on the show? Fill out the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Guest Suggestion Form!⁠
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    1 時間 15 分