検索キーワード： 歴史・解説

Quando Jennifer Doudna ainda cursava a sexta série, encontrou em sua cama um exemplar de A dupla hélice, de James Watson, deixado por seu pai. Avançando pelas páginas, Doudna ficou fascinada com os bastidores da competição científica pela descoberta dos tijolinhos que constroem a vida. Motivada pela paixão de entender o funcionamento da natureza e por transformar descobertas em invenções práticas, Doudna ajudaria a realizar aquilo que o próprio James Watson, um dos descobridores da estrutura do DNA, classificara como o próximo avanço científico mais importante da biologia.

Em 1918, um novo vírus de influenza, até então restrito às aves, passou a se manifestar também em humanos. Um ano mais tarde, o saldo era de pelo menos 100 mil mortos daquela que ficaria conhecida na história como gripe espanhola, marcando o primeiro grande embate entre a ciência e uma pandemia. Em apenas dois anos o vírus matou mais pessoas do que a Aids em todo o mundo ao longo dos 24 anos desde a sua descoberta, e mais pessoas em um ano do que a peste negra ao longo de um século.

In the last half of the twentieth century, Don Thomas discovered a cure for every marrow-based disease—like leukemia, lymphoma, and sickle-cell anemia—forever changing treatment for some of the deadliest illnesses. His feats were extraordinary, earning him a Nobel Prize, and the cascade of treatments he inspired have reshaped and will continue to reshape the practice of clinical medicine. Yet no one has ever written Thomas’s courageous story.Dr. Frederick R. Appelbaum, a member of Thomas’s research team, does so for the first time.

Mark Gober dives into fundamental beliefs about health and disease. These beliefs are so fundamental, in fact, that most of us probably haven’t thought to question them. For example, do bacteria cause disease, or are they part of the body’s cleanup crew that appears at the scene of an underlying toxicity or injury? Do researchers follow the scientific method when they claim to isolate viruses and show that they cause disease in their hosts? In addition to exploring these essential questions, Gober goes a layer deeper by examining the nature of consciousness.

I once heard someone say, "You cannot aspire to be something you have never seen." This book is not only for every little Black girl out there who has dreamt of wearing a white coat and stethoscope but also for all the little Black girls who have not dreamt of it because they have never thought it possible.

The birth of psychiatry in the early nineteenth-century fundamentally changed how madness was categorized and understood. A century on, their conceptions of mental illness continue to influence our views today. Beliefs and behavior were divided up into the pathological and the healthy. The influence of religion and the supernatural became significant measures of insanity in individuals, countries, and cultures. Troubled by Faith explores these ideas about the supernatural across society through the prism of medical history.

Dispatches from the AIDS Pandemic is a unique firsthand account from three public health leaders of CDC's early response to AIDS. Drawing in part on interviews from the CDC's AIDS oral history project, the authors trace the evolution of AIDS from newly recognized disease to pandemic.

During the height of the COVID-19 pandemic, one renowned scientist, in his famous bowtie, appeared daily on major news networks such as MSNBC, NPR, the BBC, and others. Dr. Peter J. Hotez often went without sleep, working around the clock to develop a nonprofit COVID-19 vaccine and to keep the public informed. During that time, he was one of the most trusted voices on the pandemic and was even nominated for a Nobel Peace Prize for his selfless work. He also became one of the main targets of anti-science rhetoric that gained traction through conservative news media.

Six decades ago, visionary doctors achieved the impossible: the humble kidney, acknowledged since ancient times to be as essential to life as the heart, became the first human organ to be successfully replaced with a machine. Yet huge dialysis corporations, ambitious doctor-entrepreneurs, and Beltway lobbyists soon turned this medical miracle into an early experiment in for-profit medicine—and one of the nation's worst healthcare catastrophes.

It’s hard today to remember how recently cancer was a silent killer, a dreaded disease about which people rarely spoke in public. In hospitals and doctors’ offices, conversations about malignancy were hushed and hope was limited. In this deeply researched book, Elaine Schattner reveals a sea change—from before 1900 to the present day—in how ordinary people talk about cancer. From Whispers to Shouts examines public perception of cancer through stories in newspapers and magazines, social media, and popular culture.

Mescaline, LSD, and psilocybin mushrooms. There’s been a lot of discussion in the medical world lately about the potential benefits of these and other drugs for certain medical conditions, such as anxiety and depression. As we consider the place of psychedelics in the future, we can draw insight and guidance from the history of how psychedelics have been described, sought after, applied, and prohibited over the centuries. Erika Dyck, professor of history at the University of Saskatchewan, introduces you to the world of hallucinogens.