Psychadelic-assisted therapy remains one of the hottest (and most controversial) topics in the mental health space today — and in this episode, you’re going to hear from a board-certified physician who has not only tried it but is calling it “the biggest breakthrough in mental health treatment in a generation.” That’s Dr. Sara (Gottfried) Szal, Director of Precision Medicine at the Marcus Institute of Integrative Health at Thomas Jefferson University, and multiple New York Times bestselling author. She’s a Harvard-educated medical doctor who treats professional athletes and executives alike, and I loved getting to hear about how MDMA-assisted therapy has been transformative on her journey to healing trauma. But first, here’s some context.

Only about 30% of people eventually recover from PTSD with treatment — so clearly, we’re missing a piece of the puzzle. The question is: Are psychedelics that missing piece? Multiple trials have shown participants who were given MDMA-assisted therapy for their PTSD experienced a significant reduction in the severity of the symptoms compared to people who were just given a placebo pill with therapy. In fact, in one 2023 trial, 71% of patients no longer met the diagnostic criteria for PTSD, and almost 50% were considered in remission 18 weeks after they started MDMA-assisted therapy. Of people who got the placebo with therapy, only 48% didn’t meet the diagnostic criteria anymore and 21% were in remission. Another meta-analysis found that psychedelic-assisted therapy can significantly reduce anxiety and depression, both of which often co-occur in people with PTSD.

Psychedelics aren’t for everyone, and there are risks to consider with taking any substance. The first meta-analysis that examined the safety of psychedelics in a medical context, which looked at 30 studies and was published in May of this year, revealed that in over 1,000 cases where psychedelic substances were administered to people, there were only nine serious adverse events. Most of the side effects were temporary symptoms like elevated heart rate, nausea, and lower appetite.

While Dr. Gottfried Szal shared her transformative experience with psychedelic-assisted therapy, we discussed:

• Is MDMA good for trauma?
• Has MDMA been approved for PTSD?
• How and why MDMA-assisted therapy works for PTSD
• What are the results of psychedelic-assisted therapy?
• What is happening in your brain when you add MDMA to a therapy session?
• Can psychedelic-assisted therapy be done virtually, or does it have to be in person?
• How to find psychedelic-assisted therapy near you
• The importance of finding a therapist you trust when using psychedelics
• How setting and environment play a key role in reaping the benefits of psychedelic-assisted therapy

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