In today's episode of The Fundamentals, we talk with Dr. John Ayanian, director of the U-M Institute for Healthcare Policy and Innovation. Dr. Ayanian's research explores underlying factors that contribute to persistent health disparities between minoritized groups and their white counterparts, as well as strategies for ending inequity in health care and improving overall health outcomes for everyone.

Episode Transcript

Learn more about The Fundamentals

The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Spotify, or wherever you listen to podcasts.

Hosted on Acast. See acast.com/privacy for more information.

Recently, interest in psychedelic research has seen a resurgence, strengthened by better designed and controlled clinical trials and the use of neuroimaging, examining psychedelics' potential therapeutic use for PTSD, addiction, anxiety, and depression. On today’s episode, we talk with Dr. George Mashour, professor of anesthesiology and pharmacology and founder of the Michigan Psychedelic Center about using rigorous scientific methods to unlock the mysteries of psychedelics and investigate their potential as therapeutics.

Episode Transcript

Learn more about the Global Psychedelic Survey 2025, launching 5/1/25

Learn more about The Fundamentals

The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Spotify, or wherever you listen to podcasts.

Hosted on Acast. See acast.com/privacy for more information.

There are an estimated 86 billion neurons in the human brain. Neuroscientists are actively exploring the importance of single or small groups of neurons versus networks of billions of neurons in the processing of sensory information, storage of memories, generation of movement, and everything else the brain does. Until recently, it simply wasn't possible to study billions of neurons at once. In today's episode, we talk with U-M's Dr. Anne Draelos, assistant professor of biomedical engineering and assistant professor of computational medicine and bioinformatics, who is using A.I. and bioinformatics to reveal the hidden networks of the brain, and exploring how gaining this understanding could improve lives.

Episode Transcript

Dr. Anne Draelos

Draelos Lab

Learn more about The Fundamentals

The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Spotify, or wherever you listen to podcasts.

Hosted on Acast. See acast.com/privacy for more information.

People with diabetes often have a host of other conditions including cardiovascular disease and kidney disease driven by inflammation. On today's episode, we talk with Dr. Katherine Gallagher, professor of surgery, professor of microbiology and immunology, and the Leland Ira Doan Research Professor of Vascular Surgery at U of M, who is looking at how epigenetics - the influence of environmental factors and behaviors impact on gene expression - might explain changes in the immune system in people with cardiovascular disease, diabetes, and other conditions related to inflammation.

Episode Transcript

Dr. Katherine Gallagher

Learn more about The Fundamentals

The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Spotify, or wherever you listen to podcasts.

Hosted on Acast. See acast.com/privacy for more information.

Today on The Fundamentals, we have a conversation with Dr. Sonya Wolf-Fortune, Assistant Professor of Pharmacology, whose work focuses on investigating the underlying mechanisms of psoriasis, diabetes, and other inflammatory conditions. Dr. Wolf-Fortune is trying to uncover what sets off the cascades of inflammation related to these conditions and related diseases.

Episode Transcript

Dr. Wolf-Fortune Profile

Learn more about The Fundamentals

The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Spotify, or wherever you listen to podcasts.

Hosted on Acast. See acast.com/privacy for more information.

A recent University of Michigan study found that around 20% of cervical cancer cases and cervical cancer-related deaths could be avoided if every eligible person was screened. U-M researcher, Dr. Diane Harper is hoping to lower the barriers to cervical cancer screening by making it more convenient and less expensive. How? By empowering patients with the tools and knowledge needed to collect their own samples at home for testing. This approach has the potential to greatly increase the number of people who are screened overall, and would be transformative in advancing health equity and accessibility for cervical cancer screening.

Episode Transcript

Dr. Diane Harper Profile

Learn more about The Fundamentals

The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Spotify, or wherever you listen to podcasts.

Hosted on Acast. See acast.com/privacy for more information.

The main cause of death due to opioid overdose is respiratory depression. In other words, the brain of a person under the influence of opioids can simply forget to breathe. In today’s episode, we talk with Dr. Erica Levitt, associate professor in the Departments of Pharmacology and Anesthesiology at University of Michigan Medical School, who is trying to explain this connection, with the hope of maintaining the powerful pain relieving effects of opioids without their potentially deadly effects.

Episode Transcript

Dr. Erica Levitt Profile

Learn more about The Fundamentals

The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Spotify, or wherever you listen to podcasts.

Hosted on Acast. See acast.com/privacy for more information.

Welcome to Season 3 of The Fundamentals. We're starting this season with a conversation about AI: How could AI potentially revolutionize healthcare delivery? The application of computer algorithms to medical knowledge has a long history, one that has accelerated in recent years to include generative AI platforms like ChatGPT. U-M expert Dr. Cornelius James discusses how AI is touching everything from doctors’ workloads to diagnostics to medical education.

Learn more about A.I. in healthcare

Learn more about The Fundamentals

A transcript of this episode can be found here.

The Fundamentals is a part of the Michigan Medicine Podcast Network, and is produced by the Michigan Medicine Department of Communication. You can subscribe to The Fundamentals on Apple Podcasts, Spotify, or wherever you listen to podcasts.

Hosted on Acast. See acast.com/privacy for more information.