Jo Weinand, founder of Nutcase, joins Jon to share her unlikely startup story. During Canada’s COVID lockdown, boredom led her to Google how to make a delicious plant based chocolate milk. She blended cashews, cocoa, dates, and water, and accidentally launched a business. What followed: poker games, celebrity investors like Ninja and Steve Aoki, a reality show on X, and an upcoming live-streamed equity crowdfunding finale in June, with a waitlist already open for early access.

Mac Davis never planned on revolutionizing human health through gene therapy. A serial biotechnology entrepreneur, he founded Minicircle after developing a groundbreaking transient genetic enhancement platform. In this episode, Davis shares his journey from scientific researcher to innovative startup founder, discussing the potential of hormones like statin to optimize muscle health, reduce inflammation, and potentially slow aging. He explores the challenges of building a gene therapy company, early investor support from Sam Altman and Peter Thiel, and his vision of making personalized health interventions as accessible as a routine medical treatment.

NextSense CEO, Jonathan Berent, never planned on reinventing how we sleep. He was a successful Google X engineer until a fascination with brain-sensing technology pushed him to leave everything behind and found his company. Now, he develops EEG earbuds aimed at upgrading our nightly rest and well-beingbeing. In this episode, he talks about his leap from corporate engineer to entrepreneur, why going “all in” was non-negotiable, and how we can all shed self-imposed labels to unlock bigger possibilities.

Brent Polacheck, owner of Polacheck’s Jewelers, is proving that the art of generational relationship-building still drives retail success in an era of instant gratification. How do you keep customers coming back for decades and sustain a 101-year-old family business when most people shop with a single click? In this episode, Jon talks with Brent about turning his Calabasas showroom into a social destination, choosing customers who value long-term relationships, and staying ahead of market changes as Polacheck’s expands with new boutiques and prepares the next generation to continue the legacy.

Kristin Olszewski, founder of Nomadica, is bringing premium wine to aluminum cans — and major retailers are taking notes. How do you take an industry rooted in tradition and turn it on its head? Kristin Olszewski, sommelier-turned-entrepreneur, is revolutionizing the $385 billion wine industry—one aluminum can at a time.

As the founder of Nomadica, Kristin brings organic, zero-sugar, premium wine to the masses in eco-conscious packaging. In this episode, she shares how her expertise as a Michelin-starred sommelier and background in sustainable agriculture inspired her to create a brand that’s now sold in 25 states, including at Whole Foods and Total Wine, with Target on the horizon.

Kristin opens up about being laughed out of rooms early on, her secret to spotting trends like orange wine, and how she built her business her way—slow, steady, and unapologetically disruptive.

Vadim Fedotov, CEO of Bioniq, aims to personalize the supplement market by creating custom pharmaceutical-grade products. Having played basketball on the German National Team, Vadim experienced firsthand the shortcomings of conventional sports supplements. After tearing his ACL, he was prescribed various off-the-shelf vitamins and nutrients, but none provided the relief he needed. This experience made him realize that supplementation must go beyond one-size-fits-all formulas to address individual needs in real time.

Now the co-founder and CEO of Bioniq, Vadim offers supplements tailor-made to deliver precisely what your body requires. In this episode, he discusses Bioniq’s innovative AI-powered algorithm, which is built around a proprietary database of over 6 million biochemical data points. Since its launch, Bioniq and its products, Bioniq GO and Bioniq PRO, have attracted over 100,000 users, with 92% reporting significant improvements after just one supplement cycle. Vadim also shares insights on the challenges Bioniq has faced in a highly regulated market and the valuable lessons he’s learned along the way.

Mike Feldstein, Founder and CEO of Jaspr, joins the show to discuss how he transformed bulky commercial-grade air purifiers into stylish, accessible solutions for home use. With a background in disaster restoration, Mike developed a deep understanding of air quality issues and recognized the need for products that effectively capture 99.9% of ultra-fine particles, including wildfire smoke and mold. He initially designed Jaspr for family and friends, but the demand surged during the COVID pandemic, prompting him to take it to market. By focusing on innovation and quality, Jaspr now bridges the gap between commercial and consumer air purification.

In this episode, Mike emphasizes the importance of running a lean operation with small, skilled teams, which allows Jaspr to compete with larger organizations. He also discusses his early B2B clients in the dental industry, where air quality is critical, and how he learned the value of customer service during his time as an Uber driver. Mike’s journey illustrates how diverse experiences and a commitment to solving real problems can lead to a successful business in air purification.