Join Drs Anne Cross and Riley Bove as they discuss menopause in multiple sclerosis, including overlapping symptoms, hormone therapy, and why this transition shouldn't catch anyone off guard.

Relevant disclosures can be found with the episode show notes on Medscape https://www.medscape.com/viewarticle/1002583. The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Hormonal Therapies in Multiple Sclerosis: A Review of Clinical Data https://pubmed.ncbi.nlm.nih.gov/38102502/

The 2022 Hormone Therapy Position Statement of The North American Menopause Society https://pubmed.ncbi.nlm.nih.gov/35797481/

Age-Specific Effects of Hormone Therapy Use on Overall Mortality and Ischemic Heart Disease Mortality Among Women in the California Teachers Study https://pubmed.ncbi.nlm.nih.gov/20881652/

Efficacy and Safety of Fezolinetant in Moderate to Severe Vasomotor Symptoms Associated With Menopause: A Phase 3 RCT https://pubmed.ncbi.nlm.nih.gov/36734148/

Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial https://pubmed.ncbi.nlm.nih.gov/12117397/

Effects of Menopause in Women With Multiple Sclerosis: An Evidence-Based Review https://pubmed.ncbi.nlm.nih.gov/33815241/

Uhthoff's Phenomenon in Multiple Sclerosis and Neuromyelitis Optica https://pubmed.ncbi.nlm.nih.gov/25195501/

Molecular Basis of Klotho: From Gene to Function in Aging https://pubmed.ncbi.nlm.nih.gov/25695404/

Re-WRAP (Remyelination for Women at Risk of Axonal Loss and Progression): A Phase II Randomized Placebo-Controlled Delayed-Start Trial of Bazedoxifene for Myelin Repair in Multiple Sclerosis https://pubmed.ncbi.nlm.nih.gov/37739167/

Clemastine Fumarate as a Remyelinating Therapy for Multiple Sclerosis (ReBUILD): A Randomised, Controlled, Double-Blind, Crossover Trial https://pubmed.ncbi.nlm.nih.gov/29029896/

Most MS patients are women, often diagnosed during their childbearing years. Drs Anne Cross and Riley Bove discuss maternal health, IVF, birth control, and menopause when living with MS.

Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/977036). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.

Resources

Multiple Sclerosis https://emedicine.medscape.com/article/1146199-overview

Teriflunomide (Rx) https://reference.medscape.com/drug/aubagio-teriflunomide-999771

Sphingosine 1-Phosphate Receptor Modulators https://reference.medscape.com/drugs/sphingosine-1-phosphate-receptor-modulators

Natalizumab Prescribing Information https://www.tysabri.com/content/dam/commercial/tysabri/pat/en_us/pdf/tysabri_prescribing_information.pdf

Association Between Breastfeeding and Postpartum Multiple Sclerosis Relapses https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902174/

Perinatal Depression and Anxiety in Women With Multiple Sclerosis https://n.neurology.org/content/96/23/e2789

Risk Factors for Peripartum Depression in Women With Multiple Sclerosis https://journals.sagepub.com/doi/10.1177/13524585211041108

Long-Acting Reversible Contraception: Comparing Methods https://www.medscape.com/viewarticle/857253

Neonatal and Delivery Outcomes in Women With Multiple Sclerosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625744/

Familial Risk of Early- and Late-Onset Multiple Sclerosis: A Swedish Nationwide Study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373346