Joyce Lu from the University of Ottawa interviews Dr. Céline Aguer. Dr. Aguer is an assistant professor at McGill University in the Department of Physiology and principal investigator in her muscle metabolism laboratory at the Institut du Savoir Montfort in Ottawa. In this episode, Dr. Aguer shares her research on how bisphenol A (BPA), an environmental pollutant, disrupts muscle metabolism. This episode also features additional commentary by Dr. Ella Atlas, adjunct professor at the Department of Biochemistry, Microbioloy and Immunology and Health Canada Research Scientist on environmental pollutants.

Learn more

Dr. Céline Aguer: https://www.uottawa.ca/faculty-medicine/dr-celine-aguer
Dr. Ella Atlas: https://www.uottawa.ca/faculty-medicine/dr-ella-atlas

0:16 | BEaTS, Host introduction, and Background information.
0:55 | Introduction to Dr. Aguer
1:26 | How Dr. Aguer started research on pollutants and muscle metabolism,
2:54 | Current issues with BPA exposure and why studying BPA is important?
5:51 | Special Guest Dr. Ella Atlas Introduction
6:11 | Dr. Atlas' insights on BPA alternatives and avoidance
8:05 | How BPA can cause insulin resistance in muscle cells
11:15 | Other potential health impacts of BPA exposure
12:22 | Future Studies with the Aguer Lab
14:08 | Closing Remarks

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Joyce Lu (Podcast Host), Emily Wood (Writer/Editor), Ernest Ngou (Audio Master), Angela Wang (Producer)

Sahib Moga from the University of Ottawa interviews Dr. Jean-François Couture. Dr. Couture is a Full Professor and Chair in the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa. He has published over 90 papers in prestigious journals and is a leading structural biology and epigenetics expert. In this episode, Dr. Couture shares his research on the role of a non-canonical zinc finger in stabilizing Cfp1’s integration into the H3K4 methyltransferase complex COMPASS and its implications for epigenetic signaling and cancer biology.

Learn more: http://jfclab.ca/

0:05 | BEaTS and host introduction
1:00 | Introduction to Dr. Couture
1:58 | Introduction to epigenetics and structural biology
5: 55 | COMPASS complex and its role
8:14 | Novel zinc finger discovery
12:20 | Future treatments and drug development
13:15 | Conclusion

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Daniel Nguyen (Producer), Sahib Moga (Host), Ryan Zammar (Content Writer), Francesco Cortese (Post-Production)

Iman Kashif from the University of Ottawa interviewed Dr. Barbara Vanderhyden, a senior scientist in ovarian cancer research and a professor at the University of Ottawa. In this insightful episode, Dr. Vanderhyden discusses her groundbreaking research pertaining to how immune regulator NLRC5 can reshape the tumor microenvironment and increase T-cell reactivity to better recognize and respond to cancer cells. She explains the mechanisms of immune evasion in ovarian cancer and discusses how her work could pave the way for novel therapeutic approaches.

Learn more: https://www.ohri.ca/profile/vanderhydenlab/profile

1:47 | Immune Evasion and NLRC5.
4:49 | Clinical Applications of NLRC5.
6:28 | Combination Therapy with NLRC5.
9:23 | Tumor Adaptation Challenges.
12:26 | Advice for Early Career Professionals.

Music Credit/Copyright information: Copyright free, Youtube video: “DEATH NOTE - L THEME SONG (RIFTI BEATS REMIX) [No Copyright Music]”. Account: Kingdom Power Music. Published January 18, 2021. https://www.youtube.com/watch?v=AkFHNQELp3Y&ab_channel=KingdomPowerMusic

Iman Kashif (Host, Audio Master), Jacqueline Aoun (Producer), Aaya Mahdi (Content Writer), Shreya Padhy (Content Writer)

Serena George, a student from the University of Ottawa, interviewed Dr. Melissa Fernandez, an assistant professor at the School of Nutrition Sciences at the University of Ottawa. Her research focuses on understanding the impacts of digital food environments on health and nutrition, with a particular interest in food literacy, eating practices, dietary intake, and mental health. In this episode, Dr. Fernandez gives insights into the research behind one of her studies that suggests that improving cooking skills and reducing processed food use may support healthier diets and overall well-being. Following this, Serena sits down with Nicholas Goulet, a Ph.D. candidate in the School of Human Kinetics at the University of Ottawa, who shares his perspective on Dr. Fernandez's research and the insights discussed in the interview.

00:19 | Main guest introduction

00:46 | What inspired Dr. Fernandez to focus on nutrition research

01:22 | Main findings of the study, 01:58 - Dr. Fernandez on her research study

04:18 | Food agency and impact of cooking skills, 05:38 Impact of Socioeconomic background, education, and culture

07:46 | Cooking skills and mental health

09:34 | Future research recommendations

11:39 | Message to listeners and general public

13:29 | Input from PhD candidate Nicholas Goulet

14:45 | Closing remarks.

Learn more: https://www.uottawa.ca/faculty-health-sciences/nutrition/our-professors/melissa-a-fernandez.

Music credits: Guitar Beat Intro / Outro 0128 by TuesdayNight on Pixabay.com (copyright-free)

Producer: Svitlana Demchenko, Show Host: Serena George, Writer editor: Nohadra Jeorje, Audio master: Anna Pawelko

Giselle Joseph of the University of Ottawa interviews Dr. Deborah M. Siegal of the Ottawa Hospital Research Institute about how a simple change in blood collection practices in ICUs could significantly improve patient care. Dr. Siegal is a hematologist, clinician-scientist at the Ottawa Hospital Research Institute, and Associate Professor of Medicine at the School of Epidemiology and Public Health at the University of Ottawa.

Learn more: https://www.ohri.ca/profile/dsiegal

0:06 | Introduction
0:56 | Motivation behind using small-volume tubes in ICUs
3:15 | Study design and challenges
6:19 | COVID-19 and adaptations to the study
8:46 | Limitations and interpretation of results
11:23 | Next steps


Soundtrack by The Underground Drive. All rights reserved.
Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Natasha Trehan (Producer), Giselle Joseph (Host), Emma Mahoney (Content Writer), Angela Guevara (Post-Production)

Batoul Jomaa from the University of Ottawa interviews Dr. Marisa Azad and Dr. Robin Patel on behalf of her team for the TMM4950 Science Communication course about improving the diagnostic methods for periprosthetic joint infections (PJIs). Dr. Azad is a senior scientist and physician of infectious diseases at the Ottawa Hospital Research Institute and a cross-appointed assistant professor at the University of Ottawa. Dr. Azad's research focuses on exploring PJI to develop more efficient diagnostic methods. Dr. Robin Patel is a director of the Infectious Disease Research Laboratory and a clinician at the Mayo Clinic. In this episode, Dr. Azad and Dr. Patel present their findings from their research on new diagnostic methods for PJI, how diagnostic methods can improve, and important considerations regarding PJI.

Learn more: https://www.uottawa.ca/faculty-medicine/dr-marisa-azad

0:05 | Introduction to podcast
1:15 | Introduction to Dr. Azad
1:44 | Why is diagnosing PJIs so difficult and what are the current standard treatments?
4:20 | What is the BioFire Joint Infection (JI) panel and how does it work?
5:20 | What are the plans to improve the accuracy of the BioFire Joint Infection (JI) panel?
7:23 | How will antimicrobial resistance affect the prevalence of PJIs and diagnostic strategies?
9:25 | Introduction to Dr. Robin Patel
10:00 | Are PJIs typically caused by one or multiple microbes?
11:58 | Will biomaterials reduce the risk of PJIs or introduce new problems?
14:32 | Closing remarks

Credits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Batoul Jomaa (Voice), Tony Lin (Post-Production), Abha Ranjitkar (Content Generation), Sam Khanlou (Producer)

In this episode, your host, Emily Schraeder, speaks to Dr. Christian Vaillancourt, Full Professor with the Department of Emergency Medicine, University of Ottawa, and Senior Scientist at the Ottawa Hospital Research Institute. His research looks at pre-hospital care, specifically improving care and survival for cardiac arrest and trauma victims. He implemented a multi-phase protocol to allow nurses to use automated external defibrillators (AEDs) during in-hospital cardiac arrest and studied its impact on survival. His research has a major impact on the care and treatment of cardiac arrest victims in our hospitals. We also hear from Julie Considine, Deakin Distinguished Professor, who is Chair of Nursing at Eastern Health and Director of the Centre for Quality and Patient Safety Research, who gives her point of view on this protocol.

Learn more: https://www.ohri.ca/profile/cvaillancourt

1:23 | What is an AED? Why is an AED important?
3:16 | Why is the 3-minute time frame so important? Why can it take up to 12 minutes for the first shock to occur?
5:28 | Why are nurses not allowed to use AED in hospitals?
7:47 | What were the study's challenges or different opinions and views?
10:08 | From a nursing perspective, what are some strengths and weaknesses of this protocol?
12:07 | How do you expect these protocols to be implemented in the long term?
13:49 | Is there anything that you, Dr. Vaillancourt, want the listeners to know about AED use?

Soundtrack by The Underground Drive. All rights reserved. Listen more:

https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Producer: Stephanie Khoury
Show host: Emily Schraeder
Writer editor: Hannah Verge and Elizabeth Thibeault
Audio master: Stephanie Khoury and Emily Schraeder

Hosein Hosseini Abardeh, from the University of Ottawa, interviews Dr. Kusum Menon, a senior scientist at the CHEO Research Institute, to explore her research into pediatric septic shock. In this episode, we dive into critical topics such as the use of corticosteroids in managing pediatric septic shock and the challenges and benefits of using a deferred consent model for patient recruitment in clinical studies. Special guest Katie O’Hearn joins to provide additional insights into the complexities of conducting research in pediatric critical care.

Learn more: https://www.cheoresearch.ca/research/find-a-researcher/kusum-menon/

0:06 | Host introduction.
0:27 | Introduction to Dr. Menon and Katie O'Hearn
1:15 | Walking through Dr.Menon's scientific journey
2:41 | Katie O'Hearn's role in the lab
3:44 | Why are corticosteroids used for pediatric septic shock?
5:28 | Challenges faced during the double-blind septic shock pilot study.
6:14 | How were the challenges with steroid usage addressed for the study?
7:52 | What is deferred consent? Why is it necessary? And how it was employed in the study.
10:13 | Walkthrough of what happens when a child dies during the study.
13:00 | Closing Remarks

This podcast features the song "Chroma Dusk" from Top-Flow on PixaBay, which is available under a Creative Commons Zero (CC0) license. Sergio Prosvirini created it.

https://pixabay.com/music/beats-chroma-dusk-269465/

Hosein Hosseini Abardeh (Host), Aaron Reyes (Producer), Malcolm Wilson (Audio), Vincent Baron (Script Writer)